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WARNING: Cyclosporine is a drug that reduces the body's ability to fight illness/disease (an immunosuppressant), leaving patients vulnerable to infection or other problems (including cancers such as lymphoma). Using other drugs that treat organ transplant rejection along with this drug may increase these tendencies. Cyclosporine can also cause high blood pressure and kidney problems. The risk of both problems increases with higher doses and longer treatment with this drug. Psoriasis patients who have had certain previous treatments (e.g., coal tar, methotrexate, PUVA, UVB, or other radiation therapy) are at increased risk to develop skin cancer. Therefore, cyclosporine must be given only under close medical supervision. Because different brands deliver different amounts of medication, do not switch brands of cyclosporine without your doctor's permission and directions. Laboratory tests (e.g., kidney function tests, blood tests) may be performed to monitor your progress.
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